Low temperature polymorphism in 3-amino-1-propanol
نویسندگان
چکیده
منابع مشابه
(3-Aminophenyl)diphenylphosphine oxide–2-propanol (1/1)
The title compound, C(18)H(16)NOP·C(3)H(8)O, was synthesized by the reduction of (3-nitro-phen-yl)diphenyl-phosphine oxide in the presence of 2-propanol as recrystallization solvent. There are two molecules in the asymmetric unit. Each P atom is tetra-coordinated by three C and one O atom from two phenyl fragments, one aniline group and one double-bonded O atom in a distorted tetra-hedral geome...
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Mid-IR vibrational circular dichroism (VCD) and the corresponding Raman optical activity (ROA) spectra of 1-amino-2-propanol and 2-amino-1-propanol in neat solution are compared to yield insight into the dominant structural sensitivity of each technique. The ROA spectra for these isomeric compounds are quite similar while their VCD spectra are substantially different. The contrast between the r...
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This paper describes the synthesis and in vitro antimalarial activity against a P. falciparum 3D7 strain of some new 1-aryl-3-substituted propanol derivatives. Twelve of the tested compounds showed an IC(50) lower than 1 microM. These compounds were also tested for cytotoxicity in murine J774 macrophages. The most active compounds were evaluated for in vivo activity against P. berghei in a 4-da...
متن کاملEffect of 3-amino-1-propanol on the phosphatidylinositol (PI) and glycosyl phosphatidylinositol (GPI) systems of Tetrahymena.
3-Amino-1-propanol (AP), a substance replacing ethanolamine in phosphatidylethanolamine (PE) significantly reduced 32P incorporation to phosphatidylinositol (PI) and glycosyl-phosphatidylinositol (GPI) in the unicellular organism Tetrahymena pyriformis. At 10 mM, AP completely inhibited the incorporation of 32P into PI. 3H-arachidonate incorporation into PI was also inhibited, while that into d...
متن کاملInhibition of choline synthesis in young rats by 2-amino-2-methyl-propanol-1.
2-Amino-2-methylpropanol-1 and LY ,a-dimethyltriethylcholine have been found to be competitive inhibitors of choline utilization in 40 to 50 gm. male albino rats (1). The former substance apparently only antagonized the utilization of choline in the kidney’ while the latter was an antimetabelite both in the liver and kidney. The quantitative relationships between these inhibitors and choline in...
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ژورنال
عنوان ژورنال: Journal of Molecular Structure
سال: 2003
ISSN: 0022-2860
DOI: 10.1016/s0022-2860(03)00049-8